A new study confirms that exercise helps reduce a decline in neural stems cells in the hippocampus that happens to mice in middle age. This tends to happen because nerve growth factors decline as the mouse ages, and exercise slows that decline.
Pay attention to the older folks that you know, and their wit. This may be good inspiration to keep your brain working at top form as you age...
http://jap.physiology.org/cgi/content/abstract/105/5/1585